New research has identified and described a cellular process that, despite what textbooks say, has remained elusive to scientists until now—precisely how the copying of genetic material that, once started, is properly turned off. The finding concerns a key process essential to life: the transcription phase of gene expression, which enables cells to live and do their jobs.
The research, published online by the journal Science today, Nov. 26, 2020, determined that instead of attaching to a specific piece of RNA near the end of transcription and helping it unwind from DNA, Rho actually "hitchhikes" on RNA polymerase for the duration of transcription.
Rho is known to silence the expression of virulence genes in bacteria, essentially keeping them dormant until they're needed to cause infection. But these genes do not have any RNA sequences that Rho is known to preferentially bind. Because of that, Artsimovitch said, it has never made sense that Rho looks only for specific RNA sequences, without even knowing if they are still attached to RNA polymerase.
Read the Article: https://phys.org/news/2020-11-revealing-secret-key-cellular-refutes.html
ΚΟΥΡΗΤΗΣ: ΚΑΙ ΟΜΩΣ ΕΧΟΥΜΕ ΤΟΥΣ ΝΟΜΙΚΑ ΑΝΕΥΘΥΝΟΥΣ ΝΑ ΔΗΜΙΟΥΡΓΟΥΝ "ΕΜΒΟΛΙΑ" RNA ΜΕ ΤΡΕΧΑ ΓΥΡΕΥΕ ΤΙ ΕΠΙΠΤΩΣΕΙΣ ΣΕ ΤΙ ΜΗΧΑΝΙΣΜΟΥΣ. ΤΑ ΑΠΟΤΕΛΈΣΜΑΤΑ ΑΥΤΗΣ ΤΗΣ ΕΡΕΥΝΑΣ ΕΛΗΦΘΗΣΑΝ ΥΠΟΨΙΝ; ΠΕΡΙΤΤΟ ΤΟ ΕΡΩΤΗΜΑ. ΣΑΦΩΣ ΟΧΙ.
The research, published online by the journal Science today, Nov. 26, 2020, determined that instead of attaching to a specific piece of RNA near the end of transcription and helping it unwind from DNA, Rho actually "hitchhikes" on RNA polymerase for the duration of transcription.
Rho is known to silence the expression of virulence genes in bacteria, essentially keeping them dormant until they're needed to cause infection. But these genes do not have any RNA sequences that Rho is known to preferentially bind. Because of that, Artsimovitch said, it has never made sense that Rho looks only for specific RNA sequences, without even knowing if they are still attached to RNA polymerase.
Read the Article: https://phys.org/news/2020-11-revealing-secret-key-cellular-refutes.html
ΚΟΥΡΗΤΗΣ: ΚΑΙ ΟΜΩΣ ΕΧΟΥΜΕ ΤΟΥΣ ΝΟΜΙΚΑ ΑΝΕΥΘΥΝΟΥΣ ΝΑ ΔΗΜΙΟΥΡΓΟΥΝ "ΕΜΒΟΛΙΑ" RNA ΜΕ ΤΡΕΧΑ ΓΥΡΕΥΕ ΤΙ ΕΠΙΠΤΩΣΕΙΣ ΣΕ ΤΙ ΜΗΧΑΝΙΣΜΟΥΣ. ΤΑ ΑΠΟΤΕΛΈΣΜΑΤΑ ΑΥΤΗΣ ΤΗΣ ΕΡΕΥΝΑΣ ΕΛΗΦΘΗΣΑΝ ΥΠΟΨΙΝ; ΠΕΡΙΤΤΟ ΤΟ ΕΡΩΤΗΜΑ. ΣΑΦΩΣ ΟΧΙ.
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